منابع مشابه
Tubby proteins prove their adaptability
Study reveals that Tubby family proteins help deliver GPCRs and other integral membrane proteins into cilia.
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The primary cilium is a paradigmatic organelle for studying compartmentalized signaling; however, unlike soluble protein trafficking, processes targeting integral membrane proteins to cilia are poorly understood. In this study, we determine that the tubby family protein TULP3 functions as a general adapter for ciliary trafficking of structurally diverse integral membrane cargo, including multip...
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ژورنال
عنوان ژورنال: The Journal of Cell Biology
سال: 2017
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.201702052